PET Imaging Centre, Division of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Br J Radiol. 2012 Aug;85(1016):e544-8. doi: 10.1259/bjr/46048428. Epub 2012 Feb 28.
With the increasing use of positron emission tomography (PET) for disease staging, follow-up and therapy monitoring in a number of oncological indications there is growing interest in the use of PET and PET-CT for radiation treatment planning. In order to create a strong clinical evidence base for this, it is important to ensure that research data are clinically relevant and of a high quality. Therefore the National Cancer Research Institute PET Research Network make these recommendations to assist investigators in the development of radiotherapy clinical trials involving the use of PET and PET-CT. These recommendations provide an overview of the current literature in this rapidly evolving field, including standards for PET in clinical trials, disease staging, volume delineation, intensity modulated radiotherapy and PET-augmented planning techniques, and are targeted at a general audience. We conclude with specific recommendations for the use of PET in radiotherapy planning in research projects.
随着正电子发射断层扫描（PET）在许多肿瘤学适应证中的疾病分期、随访和治疗监测中的应用越来越多，人们对 PET 和 PET-CT 在放射治疗计划中的应用产生了越来越大的兴趣。为了为此建立一个强大的临床证据基础，确保研究数据具有临床相关性和高质量非常重要。因此，国家癌症研究所 PET 研究网络提出了这些建议，以协助研究人员开展涉及使用 PET 和 PET-CT 的放射治疗临床试验。这些建议概述了这一快速发展领域的当前文献，包括临床试验中 PET 的标准、疾病分期、体积勾画、调强放射治疗和 PET 增强计划技术，并针对一般受众。我们以在研究项目中使用 PET 进行放射治疗计划的具体建议作为结论。
