Roe A W, Pallas S L, Hahm J O, Sur M
Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge 02139.
Science. 1990 Nov 9;250(4982):818-20. doi: 10.1126/science.2237432.
Maps of sensory surfaces are a fundamental feature of sensory cortical areas of the brain. The relative roles of afferents and targets in forming neocortical maps in higher mammals can be examined in ferrets in which retinal inputs are directed into the auditory pathway. In these animals, the primary auditory cortex contains a systematic representation of the retina (and of visual space) rather than a representation of the cochlea (and of sound frequency). A representation of a two-dimensional sensory epithelium, the retina, in cortex that normally represents a one-dimensional epithelium, the cochlea, suggests that the same cortical area can support different types of maps. Topography in the visual map arises both from thalamocortical projections that are characteristic of the auditory pathway and from patterns of retinal activity that provide the input to the map.
感觉表面图谱是大脑感觉皮层区域的一个基本特征。在雪貂中可以研究传入神经和靶标在高等哺乳动物新皮层图谱形成中的相对作用，在这些雪貂中，视网膜输入被导向听觉通路。在这些动物中，初级听觉皮层包含视网膜（以及视觉空间）的系统表征，而不是耳蜗（以及声音频率）的表征。在通常代表一维上皮组织（耳蜗）的皮层中出现二维感觉上皮组织（视网膜）的表征，这表明同一皮层区域可以支持不同类型的图谱。视觉图谱中的拓扑结构既源于听觉通路特有的丘脑皮层投射，也源于为该图谱提供输入的视网膜活动模式。
