Ploenes T, Osei-Agyemang T, Nestle U, Waller C F, Passlick B
Abt. Thoraxchirurgie der Albert-Ludwigs Universität Freiburg.
Dtsch Med Wochenschr. 2012 Mar;137(10):481-6. doi: 10.1055/s-0031-1298905. Epub 2012 Feb 28.
Malignant pleural mesothelioma (MMP) is a highly aggressive tumor arising of the pleural mesothelium. Asbestos exposure is the main factor involved in the pathogenesis of MMP and according to the late ban of this agent in 2005 the peak incidence in Europe is expected in the next twenty years. The highly aggressive behaviour of this tumor results in a poor prognosis with a mean overall survival between 7 and 9 months. Despite the progress made in diagnosis and therapy of this entity the optimal treatment remains a subject of debate. In this article we review the current state of treatment and diagnosis.
恶性胸膜间皮瘤（MMP）是一种起源于胸膜间皮的高度侵袭性肿瘤。石棉暴露是MMP发病机制中的主要因素，根据该物质在2005年的晚期禁令，预计欧洲的发病率峰值将在未来二十年内出现。这种肿瘤的高度侵袭性行为导致预后不良，平均总生存期在7至9个月之间。尽管在该疾病的诊断和治疗方面取得了进展，但最佳治疗方案仍是一个有争议的话题。在本文中，我们回顾了治疗和诊断的现状。
