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间皮瘤和石棉相关胸膜疾病。

Mesothelioma and asbestos-related pleural diseases.

作者信息

Greillier Laurent, Astoul Philippe

机构信息

Service d'ncologie Thoracique, Assistance Publique-Hôpitaux de Marseille, Faculté de Médecine, Université de la Méditerranée, Marseille, France.

出版信息

Respiration. 2008;76(1):1-15. doi: 10.1159/000127577. Epub 2008 May 8.

Abstract

At present, the use of asbestos is not regulated at a worldwide scale. Moreover, there is a latency period between asbestos exposure and the manifestations of asbestos-related diseases. Consequently, pulmonologists are still dealing with consequences of asbestos exposure, which mainly occur at the pleural surface. The aim of this review is to provide an overview of asbestos-related pleural diseases. We summarized the most relevant data for the diagnosis and the management of benign asbestos pleural effusions, pleural plaques, diffuse pleural thickening and rounded atelectasis. Special attention is dedicated to malignant pleural mesothelioma, given the challenging issues of this disease, the recent advances in its management and the dynamism of research in this area.

摘要

目前,石棉的使用在全球范围内并未受到监管。此外,石棉暴露与石棉相关疾病的表现之间存在潜伏期。因此,肺科医生仍在应对石棉暴露的后果,这些后果主要发生在胸膜表面。本综述的目的是概述石棉相关的胸膜疾病。我们总结了关于良性石棉性胸腔积液、胸膜斑、弥漫性胸膜增厚和圆形肺不张的诊断和管理的最相关数据。鉴于恶性胸膜间皮瘤这一疾病的挑战性问题、其治疗的最新进展以及该领域研究的动态性,我们对其给予了特别关注。

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