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复发性前庭病的临床特征和自然病程:一项长期随访研究。

Clinical characteristics and natural course of recurrent vestibulopathy: a long-term follow-up study.

机构信息

Department of Otolaryngology, School of Medicine, Gyeongsang National University, Jinju, South Korea.

出版信息

Laryngoscope. 2012 Apr;122(4):883-6. doi: 10.1002/lary.23188. Epub 2012 Feb 28.

Abstract

OBJECTIVES/HYPOTHESIS: To investigate the clinical characteristics and the natural course of recurrent vestibulopathy (RV).

STUDY DESIGN

Retrospective study.

METHODS

During the period April 2002 to February 2008, we reviewed the clinical records of 98 patients diagnosed with RV. All patients were approached by telephone and using a questionnaire. The analysis included age, sex distribution, natural history, pure-tone audiometry, caloric response, age at onset, and the characteristics of vertigo.

RESULTS

Median follow-up was 63.1 months (range, 24-103 months). Patients had a mean age at onset of 39 years and a mean duration of 4.2 years. An obvious female predilection was found, and unilateral caloric paresis (≥ 25%) was seen in 35%. Of the 98 patients, symptoms resolved in 82% but were unchanged in 12%. RV developed to Ménière's disease in four patients and to migraine in two. No patient with RV developed a central nervous system disease or benign paroxysmal positional vertigo during follow-up.

CONCLUSIONS

The study suggests that in the majority of cases, vertigo spontaneously resolves and that the risks of development to Ménière's disease or migraine are low.

摘要

目的/假设:研究复发性前庭病(RV)的临床特征和自然病程。

研究设计

回顾性研究。

方法

在 2002 年 4 月至 2008 年 2 月期间,我们回顾了 98 例 RV 诊断患者的临床记录。所有患者均通过电话和问卷调查进行评估。分析包括年龄、性别分布、自然病史、纯音测听、冷热反应、发病年龄和眩晕特征。

结果

中位随访时间为 63.1 个月(范围,24-103 个月)。患者的发病年龄平均为 39 岁,病程平均为 4.2 年。明显存在女性倾向,35%的患者出现单侧冷热反应减弱(≥25%)。98 例患者中,82%的症状缓解,但 12%的症状无变化。4 例 RV 发展为梅尼埃病,2 例发展为偏头痛。在随访期间,没有患者出现中枢神经系统疾病或良性阵发性位置性眩晕。

结论

研究表明,在大多数情况下,眩晕会自发缓解,且发展为梅尼埃病或偏头痛的风险较低。

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