一例5-氟尿嘧啶诱发冠状动脉痉挛的病例报告。 - Suppr

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A case report of 5-fluorouracil-induced coronary artery vasospasm.

作者信息

Connolly Suzanne, Scott Peter, Cochrane David, Harte Robert

出版信息

Ulster Med J. 2010 Sep;79(3):135-6.

PMID:22375089

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3284720/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70d8/3284720/ca932117dad4/umj7903-135a-f1.jpg

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本文引用的文献

The syndrome of 5-fluorouracil cardiotoxicity. An elusive cardiopathy.5-氟尿嘧啶心脏毒性综合征。一种难以捉摸的心脏病。

Cancer. 1993 Jan 15;71(2):493-509. doi: 10.1002/1097-0142(19930115)71:2<493::aid-cncr2820710235>3.0.co;2-c.

In vitro evidence that myocardial ischemia resulting from 5-fluorouracil chemotherapy is due to protein kinase C-mediated vasoconstriction of vascular smooth muscle.体外实验证据表明，5-氟尿嘧啶化疗引起的心肌缺血是由于蛋白激酶C介导的血管平滑肌血管收缩所致。

Cancer Res. 1993 Jul 1;53(13):3028-33.

Coronary artery spasm induced by 5-fluorouracil.

Eur Heart J. 1991 Mar;12(3):468-70. doi: 10.1093/oxfordjournals.eurheartj.a059919.

Very high endothelin plasma levels in patients with 5-FU cardiotoxicity.5-氟尿嘧啶心脏毒性患者血浆内皮素水平极高。

Ann Oncol. 1992 Jan;3(1):88. doi: 10.1093/oxfordjournals.annonc.a058084.

Letter: 5-Fluorouracil and angina.

Lancet. 1975 Feb 8;1(7902):347-8. doi: 10.1016/s0140-6736(75)91270-2.

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