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急性呼吸道感染患儿中的流感嗜血杆菌和肺炎链球菌。

Haemophilus influenzae and Streptococcus pneumoniae in children with acute respiratory infection.

作者信息

Jayanetra P, Vorachit M, Rittaporn A, Nawaniruttisai A, Suwanjutha S, Vathanophas K, Wasi C

机构信息

Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand.

出版信息

Southeast Asian J Trop Med Public Health. 1990 Jun;21(2):195-202.

PMID:2237586
Abstract

The incidence of Haemophilus influenzae and Streptococcus pneumoniae in children with acute respiratory infection (ARI) under 5 years was carried out by throat swab culture, blood culture, body fluid or tissue culture in 688 patients from a community, 744 patients from a teaching hospital in Bangkok, 766 normal children from the community and 303 children from a hospital well baby clinic. H. influenzae was found in the throats of 15-20% of patients and in the throats of 4-6% of normal children (p less than 0.001 for both hospital and community patients). Only 12/332 strains (3.6%) of H. influenzae were type b. The rest of H. influenzae were non type b. The most common biotype of H. influenzae non type b was biotype II. S. pneumoniae was found in hospital patients in highly significant numbers compared to the controls (12% vs 4%). No significant difference was observed in strains from the community patients.

摘要

对来自某社区的688例5岁以下急性呼吸道感染(ARI)儿童、曼谷一家教学医院的744例患儿、该社区的766例正常儿童以及一家医院健康婴儿诊所的303例儿童,通过咽拭子培养、血培养、体液或组织培养检测流感嗜血杆菌和肺炎链球菌的发病率。在15%-20%的患者咽部发现了流感嗜血杆菌,在4%-6%的正常儿童咽部也发现了该菌(医院和社区患者的p值均小于0.001)。在332株流感嗜血杆菌中,只有12株(3.6%)为b型。其余流感嗜血杆菌为非b型。非b型流感嗜血杆菌最常见的生物型是生物型II。与对照组相比,在医院患者中发现的肺炎链球菌数量显著更多(12% 对4%)。在社区患者的菌株中未观察到显著差异。

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