Department of Psychology II, University of Kaiserslautern, Erwin-Schrödinger-Straße, Kaiserslautern, Germany.
Brain Lang. 2012 Apr;121(1):1-11. doi: 10.1016/j.bandl.2011.12.003. Epub 2012 Feb 28.
This fMRI study investigated phonological vs. auditory temporal processing in developmental dyslexia by means of a German vowel length discrimination paradigm (Groth, Lachmann, Riecker, Muthmann, & Steinbrink, 2011). Behavioral and fMRI data were collected from dyslexics and controls while performing same-different judgments of vowel duration in two experimental conditions. In the temporal, but not in the phonological condition, hemodynamic brain activation was observed bilaterally within the anterior insular cortices in both groups and within the left inferior frontal gyrus (IFG) in controls, indicating that the left IFG and the anterior insular cortices are part of a neural network involved in temporal auditory processing. Group subtraction analyses did not demonstrate significant effects. However, in a subgroup analysis, participants performing low in the temporal condition (all dyslexic) showed decreased activation of the insular cortices and the left IFG, suggesting that this processing network might form the neural basis of temporal auditory processing deficits in dyslexia.
这项 fMRI 研究通过德语元音长度辨别范式（Groth、Lachmann、Riecker、Muthmann 和 Steinbrink，2011），调查了发展性阅读障碍中的语音与听觉时间处理。该研究收集了阅读障碍者和对照组在执行两种实验条件下的元音时长同异判断时的行为和 fMRI 数据。在时间条件下，而不是在语音条件下，两组被试的前脑岛皮层双侧以及对照组的左侧额下回（IFG）均观察到了血流动力学脑激活，表明左侧 IFG 和前脑岛皮层是参与听觉时间处理的神经网络的一部分。组间减法分析未显示出显著的影响。然而，在亚组分析中，在时间条件下表现较差的参与者（所有阅读障碍者）表现出脑岛皮层和左侧 IFG 的激活减少，表明该处理网络可能是阅读障碍中听觉时间处理缺陷的神经基础。
