School of Materials Science and Engineering, Nanyang Technological University, Singapore 639798, Singapore.
Small. 2012 May 7;8(9):1336-40. doi: 10.1002/smll.201102258. Epub 2012 Feb 29.
A simple, convenient, and efficient method for highly sensitive Raman detection is made by using a Au nanoparticle (AuNP)-embedded polydimethylsiloxane (PDMS) elastomer, referred to as AuNP-PDMS. When this AuNP-PDMS layer is applied to a surface, it can dramatically enhance the Raman signal of detected molecules. Moreover, it can be used for sensitive chemical imaging on solid substrates. As a proof of concept, patterned chemical images of p-aminothiophenol and methylene blue on a Ag substrate are obtained after this chemically patterned Ag substrate is covered by AuNP-PDMS.
一种简单、方便、高效的高灵敏度拉曼检测方法是使用嵌入金纳米粒子（AuNP）的聚二甲基硅氧烷（PDMS）弹性体，称为 AuNP-PDMS。当这种 AuNP-PDMS 层应用于表面时，可以显著增强被检测分子的拉曼信号。此外，它还可以用于固体基底上的灵敏化学成像。作为概念验证，在经过化学图案化的 Ag 基底上覆盖 AuNP-PDMS 后，得到了 p-氨基苯硫酚和亚甲基蓝在 Ag 基底上的图案化化学图像。
