Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea.
Small. 2012 May 7;8(9):1442-8. doi: 10.1002/smll.201102335. Epub 2012 Feb 29.
A surface-plasmon-coupling-mediated sensor system is developed based on Au nanoparticles tagged with a coordinative dipycolylamine and lipoyl-anchored naphthalimide derivative (AuNP@DPA). The AuNPs with tailored ligands exhibit distinct sensing activity via sequential assembly into nanoparticle aggregates induced by metal ion complexing, and disassembly in the presence of pyrophosphate (PPi) anions, which is accompanied by a swift, reversible color change due to a surface plasmon resonance coupling effect. It is found that divalent metal ions are more effective than mono- or tri-valent ions in the aggregate formation process, Mn(2+)-induced aggregates are more sensitive to the capture of PPi anions than other AuNP aggregates, and the disassembly upon anion complexation exhibits a highly selective response. The AuNP@DPA-based molecular recognition system also demonstrates a viable performance for the detection of total selective metal ions present in different types of water analytes.
基于标记有配位二吡咯烷和脂酰基连接的萘酰亚胺衍生物的 Au 纳米粒子（AuNP@DPA），开发了一种表面等离子体耦合介导的传感器系统。通过顺序组装成由金属离子络合诱导的纳米颗粒聚集体，以及在焦磷酸根（PPi）阴离子存在下解组装，具有定制配体的 AuNPs 表现出独特的传感活性，这伴随着由于表面等离子体共振耦合效应而发生的快速、可逆的颜色变化。研究发现，二价金属离子比单价或三价离子在聚集体形成过程中更有效，Mn（2+）诱导的聚集体对 PPi 阴离子的捕获比其他 AuNP 聚集体更敏感，并且在阴离子络合时的解组装表现出高度选择性的响应。基于 AuNP@DPA 的分子识别系统还展示了在不同类型水分析物中存在的总选择性金属离子的可行检测性能。
