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唇腭裂患者的眼科相关考量

Ophthalmic considerations in cleft lip and palate patients.

作者信息

Anchlia Sonal, Rao Krishna Shama, Bonanthaya Krishnamurthy, Anupama B, Nayak I Vittal

出版信息

J Maxillofac Oral Surg. 2011 Mar;10(1):14-9. doi: 10.1007/s12663-010-0058-z. Epub 2011 Mar 25.

Abstract

Cleft lip and palate (CL and P) represents the second most frequently occurring congenital deformity after clubfoot deformity. CL and P could be associated with many other structural abnormalities of the adjacent vital structures of the face. In this study, an attempt was made to identify the abnormalities of the ocular structures seen in patients with isolated CL and P as well as in those with syndromic CL and P. Of the 322 patients with cleft lip and palate screened, 27 (8.3%) had ocular abnormalities. Totally 47 ocular defects were identified in 27 patients. Abnormalities of the eyelid were the commonest accounting for 22% of the total defects (11/47), which includes symblepharon, ectropion, lid colobomas, euryblepharon and ptosis. Second commonest abnormality was squint 8/47 (17%) followed by orbital defects 8/47 (17%) (Telecanthus and Hypertelorism). Abnormalities of the nasolacrimal apparatus 3/47 (6%), refractive errors 7/47 (15%), dermoids 4/47 (6%), cataract 2/47 (4%) and retinal colobomas 2/47 (4%) constituted the rest. Thus, children with cleft lip and palate should be assessed as soon as possible after birth by a multidisciplinary team involving the Pediatrician, Ophthalmologist and specialists from Maxillofacial, ENT and Plastic surgery. The medical problems in this group of children are global and therefore, should not be looked at in isolation.

摘要

唇腭裂是继足内翻畸形之后第二常见的先天性畸形。唇腭裂可能与面部相邻重要结构的许多其他结构异常相关。在本研究中,我们试图确定单纯性唇腭裂患者以及综合征性唇腭裂患者眼部结构的异常情况。在筛查的322例唇腭裂患者中,27例(8.3%)存在眼部异常。27例患者共发现47处眼部缺陷。眼睑异常最为常见,占总缺陷的22%(11/47),包括睑球粘连、睑外翻、睑裂缺损、睑裂增宽和上睑下垂。第二常见的异常是斜视,占8/47(17%),其次是眼眶缺陷,占8/47(17%)(内眦间距增宽和眼距过宽)。鼻泪管装置异常占3/47(6%),屈光不正占7/47(15%),皮样囊肿占4/47(6%),白内障占2/47(4%),视网膜裂孔占2/47(4%)。因此,唇腭裂患儿出生后应尽快由包括儿科医生、眼科医生以及颌面外科、耳鼻喉科和整形外科专家在内的多学科团队进行评估。这组儿童的医疗问题是全身性的,因此不应孤立看待。

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