Yaman Aylin, Saatçi Pinar, Arikan Gül, Soylu Alper, Saatçi A Osman, Kavukçu Salih
Department of Ophthalmology, Dokuz Eylül University Faculty of Medicine, Izmir, Turkey.
Turk J Pediatr. 2009 Jul-Aug;51(4):350-3.
The aim of this study was to evaluate ocular findings in children with nonsyndromic cleft lip and palate. Fifty-seven consecutive patients with cleft lip and/or palate seeking orthodontic treatment during 2006 were examined prospectively from an ophthalmological standpoint. Mean age of the patients was 9.2 years (range: 15 days to 18 years). Of the 57 children in total, five cases (8.7%) had cleft lip, six cases (10.5%) had isolated cleft palate and 46 cases (80.7%) had both cleft lip and palate. Thirty-seven of 46 cases with cleft lip and palate were unilateral and 20 were bilateral. Eleven of the 57 patients (19.1%) had ocular findings including congenital nasolacrimal duct obstruction (5 patients), ptosis (1 patient), bilateral iris coloboma (1 patient), dermoid tumor (1 patient), vernal conjunctivitis (1 patient), and esophoria (1 patient). Twenty patients (35%) had one or more systemic abnormalities such as motor mental retardation, hearing loss, syndactylia, growth retardation, double urinary tract, vesicoureteral reflux, penile nevus, hypospadias, non-redundant testis, inguinal hernia, mitral valve prolapsus, ventricular septal defect, complete right bundle branch block, and hirsutism. Though not very often, cleft lip and palate patients may have several associated ocular changes, and these patients should also be examined by ophthalmologists.
本研究的目的是评估非综合征性唇腭裂患儿的眼部表现。从眼科角度对2006年期间连续57例寻求正畸治疗的唇裂和/或腭裂患者进行了前瞻性检查。患者的平均年龄为9.2岁（范围：15天至18岁）。在总共57名儿童中，5例（8.7%）为唇裂，6例（10.5%）为单纯腭裂，46例（80.7%）为唇腭裂。46例唇腭裂患者中，37例为单侧，20例为双侧。57例患者中有11例（19.1%）有眼部表现，包括先天性鼻泪管阻塞（5例）、上睑下垂（1例）、双侧虹膜缺损（1例）、皮样瘤（1例）、春季结膜炎（1例）和内斜视（1例）。20例患者（35%）有一种或多种全身异常，如运动智力发育迟缓、听力丧失、并指畸形、生长发育迟缓、重复尿道、膀胱输尿管反流、阴茎痣、尿道下裂、睾丸未降、腹股沟疝、二尖瓣脱垂、室间隔缺损、完全性右束支传导阻滞和多毛症。尽管不太常见，但唇腭裂患者可能有多种相关的眼部变化，这些患者也应由眼科医生进行检查。
