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机械性应激是化脓性汗腺炎的重要致病因素吗?

Is mechanical stress an important pathogenic factor in hidradenitis suppurativa?

机构信息

Department of Dermatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

出版信息

Exp Dermatol. 2012 Mar;21(3):176-7. doi: 10.1111/j.1600-0625.2012.01443.x.

DOI:10.1111/j.1600-0625.2012.01443.x
PMID:22379963
Abstract

Hidradenitis suppurativa (HS) is a chronic of recurrent, inflammatory, follicular disease that usually presents after puberty with painful deep-seated, inflamed lesions in the inverse skin areas of the body. It has been hypothesized that mechanical pressure or friction is a risk factor for HS. We describe the case of a man with a lower leg amputation who presented HS-like lesions on his leg stump after wearing a leg prosthesis. Although pilonidal sinus-like disease could not be excluded, we diagnosed him with HS-like lesions, induced by prosthesis-related friction. We argue that this case supports the concept that mechanical friction and a warm humid microclimate by occlusion contribute to HS development.

摘要

化脓性汗腺炎(HS)是一种慢性复发性、炎症性、滤泡疾病,通常在青春期后出现,表现为身体屈侧部位疼痛性、深部、炎症性病变。有人假设机械性压力或摩擦是 HS 的一个危险因素。我们描述了一例小腿截肢患者,在佩戴假肢后残肢出现类似 HS 的病变。虽然不能排除藏毛窦样疾病,但我们诊断为与假体相关的摩擦引起的类似 HS 的病变。我们认为这种情况支持这样一种观点,即机械性摩擦和闭塞引起的温暖潮湿的微环境有助于 HS 的发展。

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