Kluger Nicolas, Guillem Philippe, Kivivuori Minttu, Isoherranen Kirsi
Department of Dermatology, Allergology and Venereology, Helsinki University Central Hospital, Helsinki, Finland.
Service de chirurgie adulte, clinique du Val-d'Ouest, Ecully, France.
Skin Appendage Disord. 2020 Jan;6(1):37-40. doi: 10.1159/000503153. Epub 2019 Oct 10.
Hidradenitis suppurativa (HS) is a chronic and recurrent inflammatory skin disorder affecting mainly the areas rich in apocrine sweat glands, such as the axillae, groins and buttocks. The role of mechanical pressure and friction due to clothing in the pathogenesis of HS lesions has been previously stressed. Here, we report 2 middle-aged men who presented with HS lesions/HS-like lesions on their amputation stump and review 2 additional cases from the literature. Management was challenging as 2 patients needed tumor necrosis αinhibitor while deroofing/surgery was the option for the 2 others. These cases highlight that mechanical pressure and friction are environmental factors that can play a role in the pathogenesis of HS lesions.
化脓性汗腺炎(HS)是一种慢性复发性炎症性皮肤病,主要累及富含顶泌汗腺的区域,如腋窝、腹股沟和臀部。先前已强调过衣物引起的机械压力和摩擦在HS皮损发病机制中的作用。在此,我们报告2例在截肢残端出现HS皮损/类HS皮损的中年男性,并复习文献中的另外2例病例。由于2例患者需要使用肿瘤坏死因子α抑制剂,而另外2例患者则选择了切开引流/手术,因此治疗颇具挑战性。这些病例表明,机械压力和摩擦是可在HS皮损发病机制中起作用的环境因素。