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南非的辅助生殖技术:南非辅助生殖技术注册处产生的初步结果。

Assisted reproductive technology in South Africa: first results generated from the South African Register of Assisted Reproductive Techniques.

机构信息

Department of Obstetrics and Gynaecology, Groote Schuur Hospital and Faculty of Health Sciences, UCT.

出版信息

S Afr Med J. 2012 Feb 23;102(3 Pt 1):167-70. doi: 10.7196/samj.5311.

Abstract

OBJECTIVE

We present the first report from the South African Register of Assisted Reproductive Techniques.

METHODS

All assisted reproductive technology (ART) centres in South Africa were invited to join the register. Participant centres voluntarily submitted information from 2009 on the number of ART cycles, embryo transfers, clinical pregnancies, age of female partners or egg donors, and use of fertilisation techniques. Data were anonymised, pooled and analysed.

RESULTS

The 12 participating units conducted a total of 4 512 oocyte aspirations and 3 872 embryo transfers in 2009, resulting in 1 303 clinical pregnancies. The clinical pregnancy rate (CPR) per aspiration and per embryo transfer was 28.9% and 33.6%, respectively. Fertilisation was achieved by intracytoplasmic sperm injection in two-thirds of cycles. In most cycles, 1 - 2 embryos or blastocysts were transferred. Female age was inversely related to pregnancy rate.

CONCLUSION

The register achieved a high rate of participation. The reported number of ART cycles covers approximately 6% of the estimated ART demand in South Africa. The achieved CPRs compare favourably with those reported for other countries.

摘要

目的

我们报告了南非辅助生殖技术注册处的第一份报告。

方法

我们邀请南非所有辅助生殖技术(ART)中心加入该注册处。参与中心自愿提交了 2009 年以来的信息,包括 ART 周期、胚胎移植、临床妊娠、女性伴侣或卵子捐赠者的年龄以及受精技术的使用情况。数据经过匿名处理、汇总和分析。

结果

12 个参与单位在 2009 年共进行了 4512 次卵母细胞抽吸和 3872 次胚胎移植,产生了 1303 次临床妊娠。每次抽吸和每次胚胎移植的临床妊娠率(CPR)分别为 28.9%和 33.6%。三分之二的周期采用胞浆内单精子注射受精。在大多数周期中,移植了 1-2 个胚胎或囊胚。女性年龄与妊娠率呈负相关。

结论

该注册处的参与率很高。报告的 ART 周期数量约占南非估计的 ART 需求的 6%。获得的 CPR 与其他国家报告的结果相当。

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