Department of Urology, University of Dicle, Diyarbakır, Turkey.
Urology. 2012 May;79(5):1048-51. doi: 10.1016/j.urology.2012.01.019. Epub 2012 Mar 3.
To examine the relationship between the mean platelet volume (MPV) and varicocele to clarify the etiopathogenesis of varicocele.
MPV levels were measured in 60 varicocele subjects (group I) and 57 healthy controls (group II) from 2009-2010. Ages were similar between the 2 groups. The diagnosis of varicocele was based on the findings from both physical examination and color Doppler ultrasound.
The average patient age at the time of examination was 28.12 ± 6.4 years in group I and 28.10 ± 5.8 in group II. MPV levels were statistically significantly higher in group I than in group II (P < .001). Positive correlations were found between MPV and varicocele grade as between MPV and diameter of left spermatic vein (P < .05).
The increase in MPV is independent of the disease, and the increase in varicocele grade is associated with higher MPV in varicocele patients. On the basis of the importance of the vascular component in the pathophysiology of varicocele, we would suggest conducting more studies with platelets in varicocele patients.
探讨血小板平均体积(MPV)与精索静脉曲张之间的关系,以阐明精索静脉曲张的发病机制。
测量了 2009-2010 年 60 例精索静脉曲张患者(I 组)和 57 例健康对照者(II 组)的 MPV 水平。两组年龄相似。精索静脉曲张的诊断基于体格检查和彩色多普勒超声检查的结果。
I 组患者检查时的平均年龄为 28.12±6.4 岁,II 组为 28.10±5.8 岁。I 组的 MPV 水平明显高于 II 组(P<.001)。MPV 与精索静脉曲张程度之间呈正相关,与左侧精索静脉直径之间也呈正相关(P<.05)。
MPV 的增高与疾病无关,精索静脉曲张程度的增高与精索静脉曲张患者较高的 MPV 相关。基于精索静脉曲张病理生理学中血管成分的重要性,我们建议对精索静脉曲张患者的血小板进行更多的研究。