Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Department of Nosocomial Infection Management, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Sci Rep. 2018 Feb 12;8(1):2800. doi: 10.1038/s41598-018-21313-0.
Varicocele is a common abnormality, but the conventional microsurgical subinguinal varicocelectomy (CMSV) has some disadvantages. We invented Modified Inguinal Microscope-Assisted Varicocelectomy (MIMV) under local anesthesia. This study aims to evaluate MIMV by comparing it to CMSV in operating duration, time to return to normal activity, postoperative complications, achievement of natural pregnancy and improvement of semen quality for patients with infertility, pain score for those with scrotal pain, and so on. We enrolled 3089 patients who underwent MIMV and 476 who underwent CMSV in our hospital. Both the operating duration and the time to return to normal activity of MIMV was shorter than that of CMSV (P < 0.001). The recurrence rate (P < 0.001) and injury rate of vas deferens (P = 0.011) after MIMV were lower than that after CMSV. Moreover, patients with MIMV showed higher degree of satisfaction with the surgery experience and outcome than those with CMSV (P < 0.001). However, no statistical difference was found between the two groups in scores of pain due to surgery, postoperative varicose veins diameters, reflux duration, and the postoperative complications of wound infection, hydrocele, atrophy of testis, epididymitis, and scrotal hematoma. In summary, MIMV is a promising varicocelectomy and could be applied more in clinical practice.
精索静脉曲张是一种常见的异常,但传统的经 microsurgical 腹股沟下精索静脉曲张切除术(CMSV)存在一些缺点。我们在局部麻醉下发明了改良腹股沟显微镜辅助精索静脉曲张切除术(MIMV)。本研究旨在通过与 CMSV 比较,评估 MIMV 在手术持续时间、恢复正常活动时间、术后并发症、不孕患者自然妊娠和精液质量改善、精索静脉曲张患者疼痛评分等方面的效果。我们招募了 3089 名接受 MIMV 和 476 名接受 CMSV 的患者。MIMV 的手术持续时间和恢复正常活动时间均短于 CMSV(P<0.001)。MIMV 后复发率(P<0.001)和输精管损伤率(P=0.011)均低于 CMSV。此外,MIMV 组患者对手术体验和结果的满意度高于 CMSV 组(P<0.001)。然而,两组间手术疼痛评分、术后静脉曲张直径、反流时间以及术后感染、鞘膜积液、睾丸萎缩、附睾炎和阴囊血肿等并发症无统计学差异。总之,MIMV 是一种有前途的精索静脉曲张治疗方法,在临床实践中可能会得到更广泛的应用。