Department of Andrology, Guilin People's Hospital, Guilin, China.
Department of Andrology and Sexual Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Andrology. 2019 Nov;7(6):846-851. doi: 10.1111/andr.12605. Epub 2019 Apr 10.
The correlation between the increased mean platelet volume and varicocele is controversial.
We designed this research to demonstrate the correlation relationship between varicocele and mean platelet volume by studying the changes of mean platelet volume in patients with varicocele before and after operation.
A total of 317 patients with left unilateral varicocele underwent operation, and 293 healthy adult males were enrolled in the study. We collected diagnostic data for preoperative patients through physical examination, color Doppler ultrasonography, and blood routine, and recorded the follow-up data at 6 months after operation for varicocele. Platelet indices and the degree of varicocele or the diameter of spermatic vein correlation analysis were performed. Mean platelet volume values of preoperative and 6-month postoperative were statistically evaluated.
We found that the degree of varicocele and the diameter of spermatic vein were positively correlated with mean platelet volume (p = 0.001 or p < 0.001). When the left unilateral varicocele patients and healthy subjects were compared, there was a significant increase in mean platelet volume (p = 0.003). Mean platelet volume values of 96 varicocele patients who were cured by operation for varicocele after 6 months were decreased significantly more than preoperative (p = 0.039), but 32 varicocele patients of 6-month postoperative recurrence could not prove this change (p = 0.930).
Our research proves that mean platelet volume was positively correlated with the degree of varicocele and the diameter of spermatic vein and varicocele patients showed significantly higher mean platelet volume than healthy subjects. The mean platelet volume of varicocele patients cured by operation for varicocele after 6 months was lower than before, but there was no difference in mean platelet volume between 6-month postoperative recurrent patients with preoperative.
血小板平均体积（MPV）与精索静脉曲张之间的相关性存在争议。
通过研究精索静脉曲张患者手术前后 MPV 的变化，旨在证明精索静脉曲张与 MPV 之间的相关性。
共对 317 例左侧精索静脉曲张患者进行手术，同时纳入 293 例健康成年男性作为研究对象。对术前患者进行体格检查、彩色多普勒超声及血常规等诊断数据采集，并对精索静脉曲张术后 6 个月的随访数据进行记录。对血小板参数与精索静脉曲张程度或精索静脉直径进行相关性分析，对术前及术后 6 个月的 MPV 值进行统计学评价。
我们发现精索静脉曲张程度和精索静脉直径与 MPV 呈正相关（p=0.001 或 p<0.001）。当将左侧精索静脉曲张患者与健康受试者进行比较时，发现 MPV 明显升高（p=0.003）。96 例精索静脉曲张患者经手术治疗后 6 个月精索静脉曲张治愈，其 MPV 值较术前显著降低（p=0.039），但 32 例术后 6 个月复发的精索静脉曲张患者则无法证明这种变化（p=0.930）。
本研究证明 MPV 与精索静脉曲张程度和精索静脉直径呈正相关，精索静脉曲张患者的 MPV 明显高于健康受试者。精索静脉曲张患者经手术治疗后 6 个月的 MPV 值低于术前，但术后 6 个月复发患者的 MPV 值与术前相比无差异。
