Department of Neurology and Epilepsy Center Hessen, Philipps-University, Marburg, Germany.
Epilepsy Behav. 2012 Apr;23(4):451-7. doi: 10.1016/j.yebeh.2012.01.021. Epub 2012 Mar 3.
This study evaluated the resource use of patients with epilepsy in the German district of Marburg-Biedenkopf. A cross-sectional cohort of consecutive adults with epilepsy, irrespective of seizure severity, duration of illness and epilepsy syndrome, was investigated in all health-care sectors. Costs of inpatient and outpatient treatment were derived from billing data of participating hospitals and office-based physicians. Data on socioeconomic status, course of epilepsy and further direct and indirect costs were recorded using patient questionnaires. We enrolled 366 patients from the district of Marburg-Biedenkopf and calculated annual epilepsy-specific costs of €7738 per patient. Direct costs contributed 31.1% (€2406) and indirect costs 68.9% (€5332) of the total costs. Direct medical costs were mainly due to hospitalization (33.2% of total direct costs) and anticonvulsants (26.7%). Costs of admissions were due to status epilepticus (24.4%), video-EEG monitoring (14.8%), newly diagnosed patients (14.4%) and seizure-related injuries (8.8%). Indirect costs were mainly due to early retirement (38.0%), unemployment (35.9%) and days off due to seizures (26.2%). The mean costs of epilepsy found in our study were lower than those found in studies conducted at European epilepsy centers due to the inclusion of patients in all health-care sectors.
这项研究评估了德国马尔堡-比登科普夫地区癫痫患者的资源利用情况。在所有医疗保健领域，对患有癫痫的成年患者（无论癫痫发作的严重程度、疾病持续时间和癫痫综合征如何）进行了一项横断面队列研究。住院和门诊治疗的费用是从参与的医院和门诊医生的计费数据中得出的。使用患者问卷调查记录社会经济状况、癫痫病程以及其他直接和间接费用。我们从马尔堡-比登科普夫区招募了 366 名患者，并计算出每位患者每年癫痫特异性费用为 7738 欧元。直接成本占总费用的 31.1%（2406 欧元），间接成本占 68.9%（5332 欧元）。直接医疗费用主要来自住院治疗（占总直接医疗费用的 33.2%）和抗癫痫药物（占 26.7%）。住院费用主要归因于癫痫持续状态（24.4%）、视频脑电图监测（14.8%）、新诊断患者（14.4%）和与癫痫发作相关的损伤（8.8%）。间接成本主要归因于提前退休（38.0%）、失业（35.9%）和因癫痫发作而缺勤（26.2%）。由于纳入了所有医疗保健领域的患者，我们的研究中发现的癫痫平均费用低于在欧洲癫痫中心进行的研究中的费用。
