Vodovozov A M, Ermilov V V, Petraevskiĭ A V, Kariakina N V, Somova V V
Vestn Oftalmol. 1990 Jul-Aug;106(4):69-71.
The authors analyze the findings of clinical and morphologic studies of the pathologic changes in fundus oculi tissues of 3 patients who died with senile macular dystrophy, examined in life time by ophthalmoscopic technique with transformed light. The sclera, vascular coating, retina, macula retinae, optic nerve region were thoroughly studied with the use of review histological, histochemical methods, selective test for amyloid, thiazine red fluorescent histochemical method, and thioflavin T fluorescence. In 2 of the 3 cases amyloid degeneration in the presence of amyloid deposits in choroid vessels, arterial plexus vessels round the optic nerve presence of amyloid deposits in choroid vessels, arterial plexus vessels round the optic nerve orifice, in Bruch's membrane and in the sclera. Retinal vessels, optic nerve and its coatings were intact. Further investigations are to follow.
作者分析了3例死于老年性黄斑营养不良患者的眼底组织病理变化的临床和形态学研究结果，这些患者生前通过变换光检眼镜技术进行了检查。使用回顾性组织学、组织化学方法、淀粉样蛋白选择性检测、硫堇红荧光组织化学方法和硫黄素T荧光对巩膜、血管膜、视网膜、视网膜黄斑、视神经区域进行了深入研究。在3例中的2例中，脉络膜血管、视神经孔周围的动脉丛血管、布鲁赫膜和巩膜存在淀粉样蛋白沉积，伴有淀粉样变性。视网膜血管、视神经及其被膜完好无损。后续将进行进一步研究。
