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临床实践指南:突发性聋。

Clinical practice guideline: sudden hearing loss.

机构信息

Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan 48202, USA.

出版信息

Otolaryngol Head Neck Surg. 2012 Mar;146(3 Suppl):S1-35. doi: 10.1177/0194599812436449.

DOI:10.1177/0194599812436449
PMID:22383545
Abstract

OBJECTIVE

Sudden hearing loss (SHL) is a frightening symptom that often prompts an urgent or emergent visit to a physician. This guideline provides evidence-based recommendations for the diagnosis, management, and follow-up of patients who present with SHL. The guideline primarily focuses on sudden sensorineural hearing loss (SSNHL) in adult patients (aged 18 and older). Prompt recognition and management of SSNHL may improve hearing recovery and patient quality of life (QOL). Sudden sensorineural hearing loss affects 5 to 20 per 100,000 population, with about 4000 new cases per year in the United States. This guideline is intended for all clinicians who diagnose or manage adult patients who present with SHL.

PURPOSE

The purpose of this guideline is to provide clinicians with evidence-based recommendations in evaluating patients with SHL, with particular emphasis on managing SSNHL. The panel recognized that patients enter the health care system with SHL as a nonspecific, primary complaint. Therefore, the initial recommendations of the guideline deal with efficiently distinguishing SSNHL from other causes of SHL at the time of presentation. By focusing on opportunities for quality improvement, the guideline should improve diagnostic accuracy, facilitate prompt intervention, decrease variations in management, reduce unnecessary tests and imaging procedures, and improve hearing and rehabilitative outcomes for affected patients.

RESULTS

The panel made strong recommendations that clinicians should (1) distinguish sensorineural hearing loss from conductive hearing loss in a patient presenting with SHL; (2) educate patients with idiopathic sudden sensorineural hearing loss (ISSNHL) about the natural history of the condition, the benefits and risks of medical interventions, and the limitations of existing evidence regarding efficacy; and (3) counsel patients with incomplete recovery of hearing about the possible benefits of amplification and hearing-assistive technology and other supportive measures. The panel made recommendations that clinicians should (1) assess patients with presumptive SSNHL for bilateral SHL, recurrent episodes of SHL, or focal neurologic findings; (2) diagnose presumptive ISSNHL if audiometry confirms a 30-dB hearing loss at 3 consecutive frequencies and an underlying condition cannot be identified by history and physical examination; (3) evaluate patients with ISSNHL for retrocochlear pathology by obtaining magnetic resonance imaging, auditory brainstem response, or audiometric follow-up; (4) offer intratympanic steroid perfusion when patients have incomplete recovery from ISSNHL after failure of initial management; and (5) obtain follow-up audiometric evaluation within 6 months of diagnosis for patients with ISSNHL. The panel offered as options that clinicians may offer (1) corticosteroids as initial therapy to patients with ISSNHL and (2) hyperbaric oxygen therapy within 3 months of diagnosis of ISSNHL. The panel made a recommendation against clinicians routinely prescribing antivirals, thrombolytics, vasodilators, vasoactive substances, or antioxidants to patients with ISSNHL. The panel made strong recommendations against clinicians (1) ordering computerized tomography of the head/brain in the initial evaluation of a patient with presumptive SSNHL and (2) obtaining routine laboratory tests in patients with ISSNHL.

摘要

目的

突发性听力损失(SHL)是一种可怕的症状,常促使患者紧急或紧急就诊于医生。本指南提供了针对出现 SHL 的患者的诊断、管理和随访的循证建议。该指南主要侧重于成年患者(18 岁及以上)的突发性感觉神经性听力损失(SSNHL)。及时识别和管理 SSNHL 可能会改善听力恢复和患者生活质量(QOL)。突发性感觉神经性听力损失影响每 100,000 人中的 5 至 20 人,美国每年约有 4,000 例新发病例。本指南适用于所有诊断或管理出现 SHL 的成年患者的临床医生。

目的

本指南的目的是为临床医生提供评估 SHL 患者的循证建议,特别强调管理 SSNHL。该小组认识到,患者因 SHL 出现非特异性、主要投诉而进入医疗保健系统。因此,指南的初步建议是在患者就诊时有效地将 SSNHL 与其他原因引起的 SHL 区分开来。通过关注质量改进的机会,该指南应提高诊断准确性,促进及时干预,减少管理差异,减少不必要的检查和影像学检查,并改善受影响患者的听力和康复结果。

结果

小组提出了强烈建议,即临床医生应(1)区分突发性听力损失患者的感觉神经性听力损失与传导性听力损失;(2)向特发性突发性感觉神经性听力损失(ISSNHL)患者介绍病情的自然病史、医疗干预的益处和风险,以及现有疗效证据的局限性;(3)向听力恢复不完全的患者提供关于听力增强和听力辅助技术以及其他支持措施的可能益处的咨询。小组建议临床医生(1)对疑似 SSNHL 患者进行双侧 SHL、SHL 反复发作或局灶性神经学发现的评估;(2)如果听力图确认 3 个连续频率的听力损失为 30dB,且病史和体格检查无法确定潜在疾病,则诊断疑似 ISSNHL;(3)通过获得磁共振成像、听觉脑干反应或听力随访,对 ISSNHL 患者进行耳蜗后病理学评估;(4)在 ISSNHL 患者初始治疗失败后未完全恢复时,给予鼓室内类固醇灌注;(5)对 ISSNHL 患者进行诊断后 6 个月内进行随访听力评估。小组建议临床医生(1)对 ISSNHL 患者初始给予皮质类固醇治疗,(2)对 ISSNHL 患者在诊断后 3 个月内给予高压氧治疗。小组建议临床医生不要常规对 ISSNHL 患者开具抗病毒药、溶栓药、血管扩张剂、血管活性物质或抗氧化剂。小组强烈建议临床医生(1)在疑似 SSNHL 患者的初始评估中不要进行头部/大脑计算机断层扫描,(2)不要对 ISSNHL 患者进行常规实验室检查。

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