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非裔美国人的哮喘问题:我们能做些什么来降低更高的发病率?

Asthma in African Americans: what can we do about the higher rates of disease?

机构信息

Respiratory Institute, Cleveland Clinic,Cleveland, OH 44195, USA.

出版信息

Cleve Clin J Med. 2012 Mar;79(3):193-201. doi: 10.3949/ccjm.79a.11016.

DOI:10.3949/ccjm.79a.11016
PMID:22383554
Abstract

African Americans not only have a higher prevalence of asthma than whites, they also are encumbered with higher rates of asthma-associated morbidity and death. Factors such as genetics, socioeconomic status, health maintenance behaviors, air quality, and obesity likely contribute in combination to these burdens. Further work is needed to better understand these complex risk factors. To remedy these disparities, we need to ensure that patients at higher risk are given proper care and the knowledge to control their asthma.

摘要

非裔美国人不仅哮喘的患病率比白人高,而且还面临着更高的哮喘相关发病率和死亡率。遗传、社会经济地位、健康维护行为、空气质量和肥胖等因素可能共同促成了这些负担。需要进一步的工作来更好地理解这些复杂的风险因素。为了弥补这些差异,我们需要确保处于高风险的患者得到适当的护理和控制哮喘的知识。

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Asthma in African Americans: what can we do about the higher rates of disease?非裔美国人的哮喘问题:我们能做些什么来降低更高的发病率?
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Beta 1, Beta 2 and Beta 3 Adrenergic Receptor Gene Polymorphisms in a Southeastern European Population.东南欧人群中β1、β2和β3肾上腺素能受体基因多态性
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Age and African-American race impact the validity and reliability of the asthma control test in persistent asthmatics.
年龄和非裔美国人种族会影响哮喘控制测试在持续性哮喘患者中的有效性和可靠性。
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B adrenergic receptor gene polymorphism effect on childhood asthma severity and response to treatment.肾上腺素能受体基因多态性对儿童哮喘严重程度及治疗反应的影响。
Pediatr Res. 2018 Mar;83(3):597-605. doi: 10.1038/pr.2017.304. Epub 2018 Jan 3.
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Mapping asthma-associated variants in admixed populations.在混合人群中定位哮喘相关变异
Front Genet. 2015 Sep 29;6:292. doi: 10.3389/fgene.2015.00292. eCollection 2015.
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