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社区环境下针对抑郁症的群体心理治疗:系统评价与荟萃分析。

Group psychological therapies for depression in the community: systematic review and meta-analysis.

机构信息

Academic Unit of Primary Care, School of Social and Community Medicine, University of Bristol, Bristol, UK.

出版信息

Br J Psychiatry. 2012 Mar;200(3):184-90. doi: 10.1192/bjp.bp.111.092049.

Abstract

BACKGROUND

Psychological therapies have been shown to be effective in the treatment of depression. However, evidence is focused on individually delivered therapies, with less evidence for group-based therapies.

AIMS

To conduct a systematic review and meta-analysis of the efficacy of group-based psychological therapies for depression in primary care and the community.

METHOD

We searched MEDLINE, Embase, PsycINFO, the Cochrane Central Register of Controlled Trials and the Cochrane Collaboration Depression, Anxiety and Neurosis Review Group database from inception to July 2010. The Cochrane risk of bias methodology was applied.

RESULTS

Twenty-three studies were included. The majority showed considerable risk of bias. Analysis of group cognitive-behavioural therapy (CBT) v. usual care alone (14 studies) showed a significant effect in favour of group CBT immediately post-treatment (standardised mean difference (SMD) -0.55 (95% CI -0.78 to -0.32)). There was some evidence of benefit being maintained at short-term (SMD = -0.47 (95% CI -1.06 to 0.12)) and medium- to long-term follow-up (SMD = -0.47 (95% CI - 0.87 to -0.08)). Studies of group CBT v. individually delivered CBT therapy (7 studies) showed a moderate treatment effect in favour of individually delivered CBT immediately post-treatment (SMD = 0.38 (95% CI 0.09-0.66)) but no evidence of difference at short- or medium- to long-term follow-up. Four studies described comparisons for three other types of group psychological therapies.

CONCLUSIONS

Group CBT confers benefit for individuals who are clinically depressed over that of usual care alone. Individually delivered CBT is more effective than group CBT immediately following treatment but after 3 months there is no evidence of difference. The quality of evidence is poor. Evidence about group psychological therapies not based on CBT is particularly limited.

摘要

背景

心理疗法已被证明对抑郁症的治疗有效。然而,证据主要集中在个体提供的疗法上,而基于群体的疗法的证据较少。

目的

对基于群体的心理疗法治疗初级保健和社区中抑郁症的疗效进行系统评价和荟萃分析。

方法

我们从建库开始至 2010 年 7 月,在 MEDLINE、Embase、PsycINFO、Cochrane 对照试验中心注册库和 Cochrane 协作抑郁症、焦虑和神经症评价组数据库中进行了检索。采用 Cochrane 偏倚风险评估方法。

结果

共纳入 23 项研究。大多数研究具有较大的偏倚风险。分析组认知行为疗法(CBT)与单纯常规护理(14 项研究)的疗效显示,组 CBT 治疗后即刻有显著效果(标准化均数差(SMD)-0.55(95%可信区间-0.78 至-0.32))。在短期(SMD=-0.47(95%可信区间-1.06 至 0.12))和中-长期随访(SMD=-0.47(95%可信区间-0.87 至-0.08))时,仍有一定的获益证据。组 CBT 与个体提供的 CBT 治疗(7 项研究)的疗效比较显示,组 CBT 治疗后即刻个体提供的 CBT 治疗具有中度疗效(SMD=0.38(95%可信区间 0.09-0.66)),但在短期和中-长期随访时无差异证据。四项研究描述了三种其他类型的群体心理治疗的比较。

结论

与单纯常规护理相比,CBT 群体治疗可使临床抑郁患者受益。个体提供的 CBT 在治疗后即刻比 CBT 更有效,但 3 个月后没有证据表明有差异。证据质量较差。非 CBT 为基础的群体心理治疗的证据尤其有限。

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