G3 (Bethesda). 2012 Feb;2(2):287-97. doi: 10.1534/g3.111.001354. Epub 2012 Feb 1.
Drosophila serrata is a member of the montium group, which contains more than 98 species and until recently was considered a subgroup within the melanogaster group. This Drosophila species is an emerging model system for evolutionary quantitative genetics and has been used in studies of species borders, clinal variation and sexual selection. Despite the importance of D. serrata as a model for evolutionary research, our poor understanding of its genome remains a significant limitation. Here, we provide a first-generation gene-based linkage map and a physical map for this species. Consistent with previous studies of other drosophilids we observed strong conservation of genes within chromosome arms homologous with D. melanogaster but major differences in within-arm synteny. These resources will be a useful complement to ongoing genome sequencing efforts and QTL mapping studies in this species.
锯齿果蝇是 montium 组的成员之一，该组包含超过 98 个物种，直到最近才被认为是 melanogaster 组的一个亚组。这种果蝇是进化数量遗传学的新兴模型系统，已被用于研究物种边界、渐变变异和性选择。尽管锯齿果蝇作为进化研究的模型具有重要意义，但我们对其基因组的了解仍然存在很大的局限性。在这里，我们提供了该物种的第一代基于基因的连锁图谱和物理图谱。与其他果蝇的先前研究一致，我们观察到与 D. melanogaster 同源的染色体臂内基因具有很强的保守性，但臂内同线性存在很大差异。这些资源将是该物种正在进行的基因组测序工作和 QTL 图谱研究的有益补充。
