Triarico Silvia, Capozza Michele Antonio, Mastrangelo Stefano, Attinà Giorgio, Maurizi Palma, Ruggiero Antonio
Unità di Oncologia Pediatrica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica Sacro Cuore, Rome, Italy.
Scuola di Specializzazione in Pediatria, Università Cattolica del Sacro Cuore, Rome, Italy.
Ann Transl Med. 2020 Mar;8(6):397. doi: 10.21037/atm.2020.02.41.
Adolescents and young adults (AYA) patients with cancer show specific biological, sociodemographic and behavioral features, with lower survival rates than younger group. Gynecologic malignancies that occur among AYA requires a multidisciplinary management and a tailored model of care, in order to enhance the early diagnosis, the adherence to the treatment, the enrollment in clinical trials, the rate of survival and the quality of life (QoL). In this article, we review the main gynecological tumors that may occur in AYA, with a focus on the clinical signs at the diagnosis and the modality of treatment. In addition, we proposed a model of multidisciplinary and personalized care for AYA with gynecological tumors, which can help the clinicians to manage the specific gynecologic concerns, such as ovarian failure, contraception, fertility, late psychosocial effects.
青少年和青年（AYA）癌症患者具有特定的生物学、社会人口学和行为特征，其生存率低于较年轻群体。AYA人群中发生的妇科恶性肿瘤需要多学科管理和量身定制的护理模式，以提高早期诊断率、治疗依从性、临床试验入组率、生存率和生活质量（QoL）。在本文中，我们回顾了可能发生在AYA人群中的主要妇科肿瘤，重点关注诊断时的临床体征和治疗方式。此外，我们提出了一种针对患有妇科肿瘤的AYA人群的多学科和个性化护理模式，这可以帮助临床医生处理特定的妇科问题，如卵巢功能衰竭、避孕、生育、后期心理社会影响。
