• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

湿性年龄相关性黄斑变性的新兴治疗方法——VEGF Trap-Eye(阿柏西普)

Emerging therapies for the treatment of wet age-related macular degeneration--VEGF Trap-Eye.

作者信息

Rejdak Robert, Szkaradek Małgorzata, Grieb Paweł, Jünemann Anselm G M

机构信息

Department of Ophthalmology, Medical University of Lublin, Lublin, Poland.

出版信息

Klin Oczna. 2011;113(10-12):376-8.

PMID:22384659
Abstract

Age-related macular degeneration (AMD) is the leading cause of blindness in the industrialized world. The most severe form of this disease is exudative AMD. It accounts for 10% of cases of AMD and is responsible for approximately 90% cases of severe vision loss due to AMD. Anti-vascular endothelial growth factor (VEGF) therapy changed the standard-of-care for this blinding disease. This article presents one promising new drug for the treatment of exudative AMD--VEGF Trap-Eye.

摘要

年龄相关性黄斑变性(AMD)是工业化国家失明的主要原因。这种疾病最严重的形式是渗出性AMD。它占AMD病例的10%,约占AMD导致严重视力丧失病例的90%。抗血管内皮生长因子(VEGF)疗法改变了这种致盲疾病的治疗标准。本文介绍了一种治疗渗出性AMD的有前景的新药——VEGF Trap-Eye。

相似文献

1
Emerging therapies for the treatment of wet age-related macular degeneration--VEGF Trap-Eye.湿性年龄相关性黄斑变性的新兴治疗方法——VEGF Trap-Eye(阿柏西普)
Klin Oczna. 2011;113(10-12):376-8.
2
Anti-VEGF agents for age-related macular degeneration.抗血管内皮生长因子药物治疗年龄相关性黄斑变性。
Expert Opin Ther Pat. 2010 Jan;20(1):103-18. doi: 10.1517/13543770902762885.
3
Current therapeutic approaches in neovascular age-related macular degeneration.新生血管性年龄相关性黄斑变性的当前治疗方法
Discov Med. 2013 Jun;15(85):343-8.
4
VEGF Trap-Eye for the treatment of neovascular age-related macular degeneration.阿柏西普眼内注射溶液用于治疗新生血管性年龄相关性黄斑变性。
Expert Opin Investig Drugs. 2009 Oct;18(10):1573-80. doi: 10.1517/13543780903201684.
5
Anti vascular endothelial growth factor sequential therapy for neovascular age-related macular degeneration: is this the new deal?抗血管内皮生长因子序贯治疗新生血管性年龄相关性黄斑变性:这是新的治疗方案吗?
Curr Med Res Opin. 2012 Mar;28(3):395-400. doi: 10.1185/03007995.2012.662153. Epub 2012 Feb 14.
6
Effects of vitreomacular adhesion on anti-vascular endothelial growth factor treatment for exudative age-related macular degeneration.玻璃体黄斑粘连对湿性年龄相关性黄斑变性抗血管内皮生长因子治疗的影响。
Ophthalmology. 2011 Jan;118(1):101-10. doi: 10.1016/j.ophtha.2010.04.015. Epub 2010 Aug 3.
7
[New drug VEGF Trap-Eye--Eylea--and its use in the treatment of age-related macular degeneration, central retinal vein occlusion, diabetic macular edema, and choroidal neovascularization secondary to pathologic myopia].[新型药物血管内皮生长因子受体融合蛋白眼用注射液(阿柏西普)及其在治疗年龄相关性黄斑变性、视网膜中央静脉阻塞、糖尿病性黄斑水肿和病理性近视继发脉络膜新生血管中的应用]
Klin Oczna. 2012;114(4):308-10.
8
Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degeneration.雷珠单抗(一种抗血管内皮生长因子抗原结合片段)作为治疗新生血管性年龄相关性黄斑变性的药物的研发。
Retina. 2006 Oct;26(8):859-70. doi: 10.1097/01.iae.0000242842.14624.e7.
9
Anti-angiogenic therapy of exudative age-related macular degeneration: current progress and emerging concepts.渗出性年龄相关性黄斑变性的抗血管生成治疗:当前进展与新观念
Trends Mol Med. 2007 Aug;13(8):345-52. doi: 10.1016/j.molmed.2007.06.005. Epub 2007 Jul 17.
10
[Monoclonal antibodies targeting VEGF in ophthalmology: the case of exudative age-related macular degeneration].[眼科中靶向血管内皮生长因子的单克隆抗体:渗出性年龄相关性黄斑变性的案例]
Med Sci (Paris). 2009 Dec;25(12):1105-7. doi: 10.1051/medsci/200925121105.