Chuvykin M B, Shestakov V L
Vopr Med Khim. 1990 Jul-Aug;36(4):69-71.
Content of pyridoxal in cerebrospinal fluid exceeded its level in blood plasma of healthy children. Transport of pyridoxal through hematoencephalic barrier was decreased in children with acute leukosis, especially, with neuroleukosis, while content of pyridoxal-5-phosphate was similar to normal values. Possible mechanisms are considered which are involved in stabilization of pyroxal-5-phosphate content in cerebrospinal fluid of patients with acute leukosis, when transport of pyridoxal was impaired in central nervous system.
健康儿童脑脊液中吡哆醛的含量超过其血浆中的水平。急性白血病患儿，尤其是神经白血病患儿，吡哆醛通过血脑屏障的转运减少，而磷酸吡哆醛的含量与正常值相似。本文探讨了急性白血病患者中枢神经系统中吡哆醛转运受损时，脑脊液中磷酸吡哆醛含量稳定的可能机制。
