Kharitonchik L A, Kodentsova V M, Vrzhesinskaia O A, Risnik V V, Spirichev V B
Vopr Med Khim. 1995 May-Jun;41(3):46-50.
As shown by many-year experience of human vitaminization with vitamin B6 and by mathematical analysis of a relationship between content of pyridoxal phosphate in blood plasma, excretion of 4-pyridoxic acid with urine and the rate of PALP-effect as well as after calculation and mathematical interpretation of statistical variations in distribution of those pyridoxal phosphate content in blood plasma and the rate of PALP-effect in man after additional vitaminization, the value of PALP-effect not exceeding 2.5 and content of PALP more than 8ng/ml in blood plasma should be recommended as a criterion of normal vitamin B6 consumption. Excretion of 4-pyridoxic acid with urine more than 60mg/h in children 5-7 years old and 70 mg/h in adults and children 9 years appear to serve as a criterion of normal vitamin B6 consumption.