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[Various characteristics of protein-synthesizing apparatus of the myocardium during total ischemia].

作者信息

Maskoliunas R K, Lekis A V, Kovalenko M I, El'skaia A V, Lukoshiavichius L Iu

出版信息

Vopr Med Khim. 1990 Jul-Aug;36(4):7-10.

PMID:2238536
Abstract

A decrease in the rate of protein synthesis as well as an increase in the synthesis time of "medium-size" polypeptide chain were detected in total rabbit myocardium ischemia, which were evaluated using rabbit myocardium cell-free protein-synthesizing systems. The decrease in the synthesis rate of total myocardial proteins was shown to depend on the state of ribosomes function. Redistribution in the pools of membrane-bound and free ribosomes as well as a decrease of polyribosomes amount in total pool of myocardial ribosomes were observed under conditions of total myocardial ischemia.

摘要

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