Takayanagi I, Takagi K
Eur J Pharmacol. 1979 May 15;55(4):397-9. doi: 10.1016/0014-2999(79)90114-6.
The effects were tested of Ca ions and Sr ions on interactions of isoprenaline and its competitive inhibitor with beta-adrenoceptors in the taenia caecum from the guinea pig. Ca ions were involved in the combination of isoprenaline with the beta-adrenoceptors but not involved in the combination of the competitive inhibitor with the beta-adrenoceptors. Sr ions could not substitute for Ca ions in the isoprenaline--receptor interaction.