磁压迫性造口术作为大鼠新的膀胱造口术技术：磁膀胱造口术。
Magnetic compression ostomy as new cystostomy technique in the rat: magnacystostomy.
机构信息
Department of Pediatric Surgery and Pediatric Urology, Medical Faculty of Dicle University, Diyarbakir, Turkey.
出版信息
Urology. 2012 Mar;79(3):738-42. doi: 10.1016/j.urology.2011.11.048.
OBJECTIVE
To report the first creation of magnetic compression cystostomy (magnacystostomy) using an easy and simple new technique in rats. Magnetic compression anastomoses (magnamosis) have been previously described for gastrointestinal, biliary, urinary, and vascular anastomoses.
METHODS
Female rats were randomized into 2 groups (n = 10 each): a magnetic cystostomy group and a formal surgical cystostomy group as the control group. In the magnetic cystostomy group, a very small cylindrical magnet was inserted into the bladder. The external magnetic ball was placed subcutaneously into the suprapubic region, and the 2 magnets were coupled together strongly. On postoperative day 20 in the magnetic cystostomy group and day 10 in the surgical cystostomy group, the rats were killed, and the cystostomies were evaluated macroscopically, histopathologically, and by mechanical burst testing.
RESULTS
In the surgical cystostomy group, 3 rats died. In the remaining rats, no evidence of complications was observed. However, mild adhesion in 1 rat in the magnetic cystostomy group and moderate adhesions in all the rats in the surgical cystostomy group were observed. No significant difference was found in burst pressure between the 2 groups (mean 162 mm Hg in the magnetic cystostomy group [n = 6] and 185 mm Hg in the surgical cystostomy [n = 5] group). However, the procedure time between the magnetic cystostomy group (7.70 ± 1.64 minutes) and surgical cystostomy group (18.50 ± 2.01 minutes) was significantly different (P < .001).
CONCLUSION
Magnacystostomy is easy and safe in the rat model and could be useful for some suprapubic cystostomy procedures in humans.
目的
报告首例利用一种简单新技术在大鼠中创建磁压缩膀胱造口术（magnacystostomy）的情况。磁压缩吻合术（magnamosis）已被先前用于胃肠道、胆道、泌尿和血管吻合术。
方法
雌性大鼠被随机分为 2 组（每组 n = 10）：磁膀胱造口术组和作为对照的传统手术膀胱造口术组。在磁膀胱造口术组中，将一个非常小的圆柱形磁铁插入膀胱。将外部磁球放置在耻骨上方的皮下区域，然后将 2 个磁铁强力耦合在一起。在磁膀胱造口术组的术后第 20 天和手术膀胱造口术组的第 10 天，处死大鼠，并对膀胱造口术进行宏观、组织病理学和机械爆破测试评估。
结果
在手术膀胱造口术组中，有 3 只大鼠死亡。在其余大鼠中，未观察到并发症的证据。然而，在磁膀胱造口术组中有 1 只大鼠出现轻度粘连，而在手术膀胱造口术组的所有大鼠中均观察到中度粘连。两组之间的爆破压力无显著差异（磁膀胱造口术组的平均爆破压力为 162mmHg [n = 6]，手术膀胱造口术组的平均爆破压力为 185mmHg [n = 5]）。然而，磁膀胱造口术组（7.70 ± 1.64 分钟）和手术膀胱造口术组（18.50 ± 2.01 分钟）之间的手术时间差异具有统计学意义（P <.001）。
结论
在大鼠模型中，磁膀胱造口术简单且安全，可能对某些耻骨上膀胱造口术程序有用。
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