Uygun Ibrahim, Okur Mehmet Hanifi, Cimen Hasan, Keles Aysenur, Yalcin Ozben, Ozturk Hayrettin, Otcu Selcuk
Department of Pediatric Surgery and Pediatric Urology, Medical Faculty of Dicle University, 21280, Diyarbakir, Turkey.
Pediatr Surg Int. 2012 May;28(5):529-32. doi: 10.1007/s00383-012-3053-2. Epub 2012 Jan 24.
Magnetic compression anastomosis is used for gastrointestinal, biliary, and urinary anastomoses. We have developed a simple magnetic compression gastrostomy technique in rats.
Animals were randomized into two groups (n = 12 each): magnetic gastrostomy (MG) and surgical gastrostomy (SG) (control). In the MG group, a magnetic insertion catheter was coupled with the first magnetic ball and introduced transorally into the stomach. A second magnetic ball was placed subcutaneously into the left upper quadrant. The two magnetic balls (4 mm) were strongly coupled together. On postoperative day (PD) 20 (MG group) and PD10 (SG group), rats were killed, gastrostomies were evaluated macroscopically and histopathologically, and mechanical burst testing was performed.
Two animals died due to suspected leaks. Macroscopic evaluation indicated no gastrostomy canal in one rat in each group. Mild adhesion was observed in two rats in the MG group. Moderate adhesion was observed in all rats in the SG group. No significant differences were observed in burst pressure between the two groups (means: MG group, 143 mmHg, n = 9; SG group, 159 mmHg, n = 8).
Magnetic compression gastrostomy can be performed easily in rats, and may be developed in future as a simple alternative to some gastrostomy procedures in humans.
磁性压缩吻合术用于胃肠道、胆道和尿路吻合。我们已在大鼠中开发出一种简单的磁性压缩胃造口术技术。
将动物随机分为两组（每组n = 12）：磁性胃造口术（MG）组和手术胃造口术（SG，对照组）。在MG组中，将磁性插入导管与第一个磁球连接，并经口引入胃内。将第二个磁球皮下放置于左上腹。将两个4毫米的磁球紧密连接在一起。在术后第20天（MG组）和第10天（SG组），处死大鼠，对胃造口进行宏观和组织病理学评估，并进行机械破裂测试。
两只动物因疑似渗漏死亡。宏观评估显示每组各有一只大鼠无胃造口通道。MG组有两只大鼠观察到轻度粘连。SG组所有大鼠均观察到中度粘连。两组之间的破裂压力无显著差异（平均值：MG组，143 mmHg，n = 9；SG组，159 mmHg，n = 8）。
磁性压缩胃造口术可在大鼠中轻松实施，未来可能发展成为人类某些胃造口术的一种简单替代方法。
