Veterinary Biomedical Sciences, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Edinburgh EH9 1QH, UK.
Vet J. 2012 Aug;193(2):545-50. doi: 10.1016/j.tvjl.2012.01.019. Epub 2012 Mar 2.
Dogs with chronic pain have a compromised quality of life. Repeatable and accurate sensory assessments form a means by which the hypersensitivity likely to reflect chronic pain may be quantified. These assessments can be applied to individuals to identify those that may benefit from improved analgesic relief. In this study four sensory assessments were evaluated in dogs presenting with a naturally occurring chronic painful condition (cranial cruciate ligament rupture, CCLR) and were compared with healthy control animals of similar age and weight. Inter-digital von Frey filament and thermal sensitivity tests revealed that the affected hind limb of dogs with CCLR was significantly more sensitive than the opposing limb. Static weight bearing and gait parameter scores were also reduced in the affected hind limb compared to the opposing hind limb of dogs with CCLR; no such differences were found between the hind limbs of healthy (control) dogs. The quantitative sensory tests permitted the differentiation of limbs affected by CCLR from healthy limbs. Dogs presenting with CCLR demonstrate objectively quantitative sensory sensitivities, which may require additional consideration in case management.
患有慢性疼痛的狗的生活质量受损。可重复且准确的感觉评估形成了一种手段，通过这种手段，可能反映慢性疼痛的超敏反应可以被量化。这些评估可以应用于个体，以确定那些可能受益于改善镇痛缓解的个体。在这项研究中，对患有自然发生的慢性疼痛疾病（十字韧带断裂，CCLR）的狗进行了四项感觉评估，并与年龄和体重相似的健康对照动物进行了比较。趾间 von Frey 细丝和热敏感性测试表明，患有 CCLR 的狗的受影响后肢比对侧肢明显更敏感。与 CCLR 狗的对侧后肢相比，静态承重和步态参数评分也降低了；在健康（对照）狗的后肢之间没有发现这种差异。定量感觉测试允许将 CCLR 影响的肢体与健康的肢体区分开来。患有 CCLR 的狗表现出客观的定量感觉敏感性，这在病例管理中可能需要额外考虑。
