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立体定向放射外科和放射治疗用小多叶准直器(MMLC)的调试。

Commissioning of mini-multi-leaf-collimator (MMLC) for stereotactic radiosurgery and radiotherapy.

机构信息

Radiation Oncology, Oklahoma University Health Sciences Center, Oklahoma City, OK 73104, USA Radiation Oncology, University of Massachusetts Memorial Medical Center Worcester, MA 01655, USA.

出版信息

J Xray Sci Technol. 2003 Jan 1;11(1):21-31.

Abstract

Commissioning of a Radionics miniature multi-leaf collimator (MMLC) for stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT) is reported. With single isocenter and multi static fields, the MMLC can provide better conformity of dose distributions to the target and/or irregularly shaped target volumes than standard arc (circular) field beams with multiple isocenters. Advantages offered by the MMLC over traditional LINAC based SRS and SRT includes greatly improved dose homogeneity to the target, reduced patient positioning time and reduced treatment time. In this work, the MMLC is attached to a Varian 2300 C/D with Varian 80-leaf multi-leaf collimator. The MMLC has 62 leaves, each measured to a width of 3.53 mm at isocenter, with fields range from 1x1 cm to less than 10 × 12 cm. Beam parameters required by the Radionics treatment planning system (XPlan version 2) for evaluating the dose include tissue maximum ratio (TMR), scatter factors (SF), off-axis ratios (OAR), output factors, penumbra function (P) and transmission factors (TF) are performed in this work. Beam data are acquired with a small stereotactic diode, standard ion chambers and radiographic films. Measured profiles of dose distribution are compared to those calculated by the software and absolute dosimetry is performed.

摘要

本文报道了一款 Radionics 微型多叶准直器(MMLC)在立体定向放射外科(SRS)和立体定向放疗(SRT)中的准直器调试。通过单一等中心点和多静态场,MMLC 可以比多等中心点的标准弧形(圆形)场束更好地使剂量分布与目标和/或不规则形状的靶区适形。与传统基于 LINAC 的 SRS 和 SRT 相比,MMLC 具有以下优势:显著提高了靶区的剂量均匀性,减少了患者定位时间和治疗时间。在这项工作中,MMLC 被安装在具有 Varian 80 叶片多叶准直器的 Varian 2300 C/D 上。MMLC 有 62 个叶片,在等中心处测量每个叶片的宽度为 3.53 毫米,照射野范围从 1x1cm 到小于 10x12cm。Radionics 治疗计划系统(XPlan 版本 2)评估剂量所需的光束参数包括组织最大比(TMR)、散射因子(SF)、离轴比(OAR)、输出因子、半影函数(P)和透射因子(TF),这些参数在本工作中进行了测量。使用小型立体定向二极管、标准电离室和射线照相胶片获取光束数据。测量的剂量分布轮廓与软件计算的轮廓进行比较,并进行绝对剂量测定。

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