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锁骨下静脉血栓形成后上肢的静脉血流动力学

Venous haemodynamics of the upper extremity after subclavian vein thrombosis.

作者信息

Lindblad B, Bornmyr S, Kullendorff B, Bergqvist D

机构信息

Department of Surgery, University of Lund, Sweden.

出版信息

Vasa. 1990;19(3):218-22.

PMID:2238816
Abstract

Late post-thrombotic complaints after subclavian vein thrombosis are reported with highly varying frequencies (8-80% severe disability). The therapeutic approach depends partly on this frequency. With the aim to evaluate late sequelae a questionnaire was answered by 26 patients with arm-shoulder symptoms leading to arm phlebography, but where the examination did not reveal any thrombi. 65% had remaining symptoms 2-9 years after the examination. 3 had to change profession. 36 patients with phlebographically shown subclavian vein thrombosis answered the same questionnaire. Only 9 (25%) had remaining symptoms and in 4 it was classified as mild, in 4 as moderate and only in 1 patient as severe leading to change of profession. Venous haemodynamics in the upper extremity were also studied in 3 groups of patients; I) healthy volunteers (n = 16 arms), II) patients with arm-shoulder disabilities with negative arm phlebography (n = 7 disabled arms, n = 7 non-disabled arms), III) patients with phlebographically verified subclavian vein thrombi (n = 10 arms with DVT, n = 8 arms without DVT). Strain gauge plethysmography was used measuring venous capacity and maximal venous outflow. Venous pressure measurements were made both with the arms in a resting position and in a military position with and without work-load. Repeat phlebography of arms with symptoms were made. Maximal venous outflow was significantly lower in arms with previous subclavian vein thrombi (p less than 0.05) and venous pressure measurements with the arm in military position was significantly higher in those arms. However, no correlation between these measurements and the degree of arm disability was noted.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

据报道,锁骨下静脉血栓形成后晚期血栓形成后症状的出现频率差异很大(8%-80%为严重残疾)。治疗方法部分取决于该频率。为了评估晚期后遗症,26例有臂-肩症状并接受了上肢静脉造影但检查未发现血栓的患者回答了一份问卷。65%的患者在检查后2至9年仍有症状。3人不得不更换职业。36例经静脉造影显示有锁骨下静脉血栓形成的患者回答了相同的问卷。只有9例(25%)仍有症状,其中4例被归类为轻度,4例为中度,只有1例严重到需要更换职业。还对3组患者的上肢静脉血流动力学进行了研究:I)健康志愿者(n = 16条手臂),II)上肢静脉造影阴性的臂-肩残疾患者(n = 7条残疾手臂,n = 7条非残疾手臂),III)经静脉造影证实有锁骨下静脉血栓的患者(n = 10条有深静脉血栓的手臂,n = 8条无深静脉血栓的手臂)。使用应变片体积描记法测量静脉容量和最大静脉流出量。在手臂处于休息位置和军姿位置时,无论有无负荷,均进行静脉压力测量。对有症状的手臂进行重复静脉造影。既往有锁骨下静脉血栓形成的手臂最大静脉流出量显著降低(p < 0.05),且这些手臂在军姿位置时的静脉压力测量值显著更高。然而,未发现这些测量值与手臂残疾程度之间存在相关性。(摘要截短于250字)

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