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[尿液中草酸钙结晶倾向的研究——实验及计算机辅助测定尿路结石形成风险的研究]

[Studies on the crystallization tendency of calcium oxalate in urine--a study of experimental and computer-assisted determination of the risk of urinary calculi formation].

作者信息

Berg W, Bothor C, Geyer H

机构信息

Klinik und Poliklinik für Urologie, Bereich Medizin der Friedrich-Schiller-Universität Jena.

出版信息

Z Urol Nephrol. 1990 Jul;83(7):347-57.

PMID:2238876
Abstract

In this study a method o the semiquantitative determination of the crystallization tendency for calcium oxalate in urine is described. It is based on the addition of a well-defined amount of ammonium oxalate (31.3 nmol) to a urine sample (30 ml). The so caused clouding of the urine is measured by a photometer 20 min later. The method guarantees an acceptable reproducibility and is simple to be performed in each clinical laboratory. The results of mathematical correlation and discriminant analysis show that the calcium concentration influences the crystallization of calcium oxalate as most of all urinary constituents. Furthermore, evidence of a high specificity of the method is given by a reclassification rate of about 80% in the discriminant analytical computation.

摘要

本研究描述了一种半定量测定尿液中草酸钙结晶倾向的方法。该方法基于向30ml尿液样本中加入明确量的草酸铵(31.3nmol)。20分钟后用光度计测量由此导致的尿液浑浊度。该方法保证了可接受的重现性,且易于在每个临床实验室进行操作。数学相关性和判别分析结果表明,钙浓度对草酸钙结晶的影响最为显著,是所有尿液成分中影响最大的。此外,判别分析计算中约80%的重新分类率表明该方法具有较高的特异性。

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