Rodgers A L, Garside J
Invest Urol. 1981 May;18(8):484-8.
We determined quantitative nucleation and growth kinetics of calcium oxalate in the presence of various combinations of urine constituents, using a continuous mixed suspension mixed product removal crystallizer and a Coulter counter. Nucleation rates of calcium oxalate from the pure component system were approximately an order of magnitude higher than those from an artificial urine. The presence of citrate inhibited nucleation rates under high conditions. The ions Na+, K+, NH4+, Cl-, and SO42- did not affect the overall kinetics in the synthetic urine. Di- and tri-hydrate products were formed, except when crystallizing from pure components, when only the thermodynamically stable monohydrate was observed.
我们使用连续混合悬浮混合产物移除结晶器和库尔特计数器，测定了在各种尿液成分组合存在的情况下草酸钙的定量成核和生长动力学。纯组分体系中草酸钙的成核速率比人工尿液中的成核速率大约高一个数量级。柠檬酸盐的存在在高条件下抑制了成核速率。Na+、K+、NH4+、Cl-和SO42-离子在合成尿液中不影响整体动力学。除了从纯组分结晶时仅观察到热力学稳定的一水合物外，还形成了二水合物和三水合物产物。
