Anesthesiology, Hospital General Universitario de Ciudad Real, 13005 Ciudad Real, Spain.
Obes Surg. 2012 May;22(5):843-6. doi: 10.1007/s11695-012-0625-0.
The laparoscopic Roux-en-Y gastric bypass (LRYGB) is the standard surgical procedure for morbidly obese patients in many centers worldwide. The gastrojejunal anastomosis (GJA) leak has a 2 % incidence and a 10 % mortality. This prospective study aims to test gastroenteric tonometry as an early warning of GJA leak risk. A nasogastric tube with tonometric capability was used to monitor gastroenteric mucosal carbon dioxide partial pressure (PgeCO2) in 32 consecutive patients during the first 24 to 72 postoperative hours after LRYGB. Sensitivity was 100 %, specificity 96.77 %, likelihood ratio 31, and area under receiver operating characteristic curve 0.984. The only early gastrojejunal leak occurred to the patient with maximal PgeCO2 (13.9 kPa) of the cohort. The remaining patients kept a PgeCO2 below 11 kPa except one; none of these developed early GJA leak. Mucosal gastroenteric tonometry may be a useful predictor of early GJA leak of the LRYGB.
腹腔镜 Roux-en-Y 胃旁路术(LRYGB)是世界许多中心治疗病态肥胖患者的标准手术方法。胃空肠吻合口(GJA)漏的发生率为 2%,死亡率为 10%。本前瞻性研究旨在测试胃肠测压作为 GJA 漏风险的早期预警指标。在 LRYGB 后 24 至 72 小时内,使用具有测压功能的鼻胃管监测 32 例连续患者的胃肠黏膜二氧化碳分压(PgeCO2)。敏感性为 100%,特异性为 96.77%,似然比为 31,受试者工作特征曲线下面积为 0.984。唯一的早期胃空肠漏发生在 PgeCO2 最高(13.9 kPa)的患者。除了 1 例患者外,其余患者的 PgeCO2 保持在 11 kPa 以下,这些患者均未发生早期 GJA 漏。黏膜胃肠测压可能是 LRYGB 早期 GJA 漏的有用预测指标。