Alam Mahboob, Bandeali Salman Jamaluddin, Shahzad Saima A, Lakkis Nasser
Memphis Veterans Affairs Medical Center, Memphis, TN, USA.
Expert Rev Cardiovasc Ther. 2012 Mar;10(3):283-91. doi: 10.1586/erc.12.8.
Despite being one of the most studied arrhythmias, there is paucity of information regarding atrial fibrillation (AF) control in the general population and the treatment strategies utilized by healthcare providers. REALISE-AF is an ongoing international registry investigating the management of AF and its control in nonhospitalized subjects. The registry has enrolled patients in 26 countries worldwide with the primary aim to determine the control of AF. This article presents a review of the initial results from the REALISE-AF registry and compares it to major practice-changing clinical trials conducted in the past. It also gives an overview of the current management strategies, recent updates in treatment and what further developments portend in the future.
尽管心房颤动(AF)是研究最多的心律失常之一,但关于普通人群中心房颤动的控制以及医疗服务提供者所采用的治疗策略的信息却很少。REALISE-AF是一项正在进行的国际注册研究,旨在调查非住院患者心房颤动的管理及其控制情况。该注册研究已在全球26个国家招募了患者,主要目的是确定心房颤动的控制情况。本文介绍了REALISE-AF注册研究的初步结果,并将其与过去进行的具有重大实践变革意义的临床试验进行了比较。它还概述了当前的管理策略、治疗方面的最新进展以及未来可能的进一步发展。