Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China.
Cerebellum. 2012 Dec;11(4):939-45. doi: 10.1007/s12311-012-0371-9.
Cerebellar hemorrhage is the least common type of intracranial hemorrhage (ICH) encountered in clinical practice, and clinical data concerning the long-term outcomes are limited. This study aimed to investigate the long-term outcomes following spontaneous cerebellar hemorrhage in a cohort of Chinese patients. This single-center observational study was carried out between 1996 and 2010 and included 72 consecutive Chinese patients with a first spontaneous cerebellar hemorrhage. Of 440 patients with primary ICH, 72 (16.4%) had primary cerebellar hemorrhage. The mean age was 67.5 ± 12.3 years and patients were predominantly male (54%). The 30-day mortality was 16.7% with Glasgow coma scale ≤ 8 as the only predictor. At 6 months, 56.7% of patients who survived the first 30 days had a persistently poor functional status with modified Rankin scale score >2. After a mean follow-up of 4.7 years, 3.3% of patients had recurrent ICH, a recurrence rate of 7.3 per 1,000 patient-years. Ischemic stroke occurred in 12% of patients, an incidence of 25.5 per 1,000 patient-years. This study provided data on the long-term outcome of post-cerebellar hemorrhage in Chinese patients.
小脑出血是临床实践中最不常见的颅内出血(ICH)类型,关于其长期预后的数据有限。本研究旨在调查中国患者自发性小脑出血后的长期预后。这是一项单中心观察性研究,于 1996 年至 2010 年进行,纳入了 72 例连续的中国自发性小脑出血患者。在 440 例原发性 ICH 患者中,72 例(16.4%)为原发性小脑出血。平均年龄为 67.5±12.3 岁,患者以男性为主(54%)。30 天死亡率为 16.7%,格拉斯哥昏迷量表≤8 是唯一的预测因素。在 30 天存活的患者中,6 个月时 56.7%的患者持续存在功能状态差,改良 Rankin 量表评分>2。平均随访 4.7 年后,3.3%的患者发生复发性 ICH,复发率为每 1000 患者年 7.3 例。12%的患者发生缺血性卒中,发生率为每 1000 患者年 25.5 例。本研究提供了中国患者小脑出血后长期预后的数据。