Takahashi M, Niwa H, Yanagita N
Department of Otorhinolaryngology, Nagoya University School of Medicine, Japan.
Acta Otolaryngol Suppl. 1990;471:39-42.
We measured PO2 values in mucoid and serous middle ear effusions (M-MEE, S-MEE) and in the middle ear mucosa of patients with otitis media with effusion (OME) and compared these values with those obtained from patients with middle ear barotrauma (MEBT). The mean and S.D. values of PO2 in M-MEE, S-MEE and MEBT effusions were 28.9 +/- 11.3, 31.5 +/- 9.5 and 37.0 +/- 15.4 mmHg, respectively; the mean and S.D. values in mucosa were 27.1 +/- 11.9, 27.0 +/- 13.2 and 32.5 +/- 1.0 mmHg, respectively. In health, PO2 values in middle ear mucosa are regulated by its blood supply, oxygen solubility in blood and the blood-to-cavity partial pressure gradient of the gas. When the Eustachian tube (ET) function is severely impaired, PO2 values in the middle ear air cavity depend on the mucosal condition, though some studies have shown a lack of relationship between ET function and PO2 values. Our results show that PO2 values in MEBT are consistently higher than in OME, suggesting that the attributable factor could be a better ET function in MEBT.
我们测量了分泌性中耳炎（OME）患者的黏液性和浆液性中耳积液（M-MEE、S-MEE）以及中耳黏膜中的氧分压（PO2）值，并将这些值与中耳气压伤（MEBT）患者的相应值进行了比较。M-MEE、S-MEE和MEBT积液中PO2的平均值和标准差分别为28.9±11.3、31.5±9.5和37.0±15.4 mmHg；黏膜中的平均值和标准差分别为27.1±11.9、27.0±13.2和32.5±1.0 mmHg。在健康状态下，中耳黏膜中的PO2值受其血液供应、血液中的氧溶解度以及气体的血腔分压差调节。当咽鼓管（ET）功能严重受损时，中耳气腔中的PO2值取决于黏膜状况，不过一些研究表明ET功能与PO2值之间缺乏关联。我们的结果表明，MEBT中的PO2值始终高于OME，这表明相关因素可能是MEBT中更好的ET功能。
