体外构建杂交病毒及其用于生产特定病毒或细胞蛋白的可能性。
Construction of hybrid viruses in vitro and their possible use for the production of specific viral or cellular proteins.
作者信息
Yaniv M
出版信息
Dev Biol Stand. 1979;42:87-91.
PMID:223926
Abstract
The use of plasmid and bacteriophage vectors for cloning of DNA segments from procaryotes and eucaryotes is described. A similar approach is being developed with DNA viruses like simian virus 40 or adenovirus 2. Such hybrid viruses may permit the amplification of specific genes and the overproduction of the corresponding proteins.
摘要
本文描述了使用质粒和噬菌体载体克隆原核生物和真核生物DNA片段的方法。类似的方法也正在应用于诸如猴病毒40或腺病毒2等DNA病毒。这种杂交病毒可能允许特定基因的扩增以及相应蛋白质的过量产生。
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