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法国铀矿矿工队列中氡及其衰变产物暴露测量相关不确定性的评估。

Assessment of uncertainty associated with measuring exposure to radon and decay products in the French uranium miners cohort.

作者信息

Allodji Rodrigue S, Leuraud Klervi, Bernhard Sylvain, Henry Stéphane, Bénichou Jacques, Laurier Dominique

机构信息

Institut de Radioprotection et de Sûreté Nucléaire (IRSN), DRPH, SRBE, Laboratoire d'Épidémiologie, BP17, 92262 Fontenay-aux-Roses Cedex, France.

出版信息

J Radiol Prot. 2012 Mar;32(1):85-100. doi: 10.1088/0952-4746/32/1/85. Epub 2012 Mar 5.

Abstract

The reliability of exposure data directly affects the reliability of the risk estimates derived from epidemiological studies. Measurement uncertainty must be known and understood before it can be corrected. The literature on occupational exposure to radon ((222)Rn) and its decay products reveals only a few epidemiological studies in which uncertainty has been accounted for explicitly. This work examined the sources, nature, distribution and magnitude of uncertainty of the exposure of French uranium miners to radon ((222)Rn) and its decay products. We estimated the total size of uncertainty for this exposure with the root sum square (RSS) method, which may be an alternative when repeated measures are not available. As a result, we identified six main sources of uncertainty. The total size of the uncertainty decreased from about 47% in the period 1956-1974 to 10% after 1982, illustrating the improvement in the radiological monitoring system over time.

摘要

暴露数据的可靠性直接影响从流行病学研究得出的风险估计的可靠性。在能够对测量不确定性进行校正之前,必须先了解它。关于职业性接触氡((222)Rn)及其衰变产物的文献表明,只有少数流行病学研究明确考虑了不确定性。这项工作研究了法国铀矿工人接触氡((222)Rn)及其衰变产物的不确定性的来源、性质、分布和大小。我们用平方根和(RSS)方法估计了这种暴露的不确定性的总大小,当无法获得重复测量值时,这可能是一种替代方法。结果,我们确定了六个主要的不确定性来源。不确定性的总大小从1956 - 1974年期间的约47%降至1982年以后的10%,这说明了放射监测系统随着时间的推移有所改进。

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