Zhao Ping, Xu Jun, Zhang Tiejun, Xu Haiyu, Niu Chenjin
Tianjin Pharmtech Co., Ltd., Tianjin 300457, China.
Zhongguo Zhong Yao Za Zhi. 2011 Dec;36(23):3380-5.
"Disease-syndromes-formulas-medicines" binding mode is benefit to reveal the scientific connotation of the compatibility and mechanism of classical prescriptions of traditional Chinese medicine (TCM). In this article, Zuojin Wan was used as a model prescription, with the etiology and pathogenesis of liver-fire invading stomach in TCM, and modern pathological and pharmacological interpretation, the compatibility, nature-flavour, channel tropism, the active substance and pharmacology of Zuojin Wan were explained, in order to reveal the compatibility, nature-flavour and channel tropism of Zuojin Wan, and to provide ideas for the development of modern compound prescription.
“病证方药”结合模式有利于揭示中医经典方剂配伍及作用机制的科学内涵。本文以左金丸为示范方剂，结合中医肝火犯胃的病因病机及现代病理、药理阐释，对方剂的配伍、性味、归经、活性物质及药理进行解读，以揭示左金丸的配伍、性味与归经，为现代复方研发提供思路。
