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用于牛受体同步化以进行定时胚胎移植并提高妊娠率的治疗方法。

Treatments for the synchronisation of bovine recipients for fixed-time embryo transfer and improvement of pregnancy rates.

作者信息

Bó Gabriel A, Peres Lucas Coelho, Cutaia Lucas E, Pincinato Danilo, Baruselli Pietro S, Mapletoft R J

机构信息

Instituto de Reproducción Animal Córdoba (IRAC), Zona Rural General Paz, 5145, Córdoba, Argentina.

出版信息

Reprod Fertil Dev. 2011;24(1):272-7. doi: 10.1071/RD11918.

DOI:10.1071/RD11918
PMID:22394969
Abstract

Although embryo transfer technology has been used commercially in cattle for many years, the inefficiency of oestrus detection, especially in recipients, has limited the widespread application of this technology. The most useful alternative to increase the number of recipients utilised in an embryo transfer program is the use of protocols that allow for embryo transfer without the need for oestrus detection, usually called fixed-time embryo transfer (FTET). Most current FTET protocols are based on progestin-releasing devices combined with oestradiol or GnRH, which control and synchronise follicular wave dynamics and ovulation. Conception rates to a single FTET have been reported to be similar to those after detection of oestrus, but pregnancy rates are higher because these treatments have increased the proportion of recipients that receive an embryo. Recent changes to treatments for FTET, such as the administration of eCG, have resulted in increased pregnancy rates and provide opportunities to make these treatments easier to perform on farm.

摘要

尽管胚胎移植技术已在奶牛商业生产中应用多年,但发情检测效率低下,尤其是在受体母牛中,限制了该技术的广泛应用。增加胚胎移植计划中使用的受体数量的最有效替代方法是采用无需发情检测即可进行胚胎移植的方案,通常称为定时胚胎移植(FTET)。目前大多数FTET方案基于释放孕激素的装置并结合雌二醇或促性腺激素释放激素(GnRH),它们控制并同步卵泡波动态和排卵。据报道,单次FTET的受胎率与发情检测后的受胎率相似,但妊娠率更高,因为这些处理增加了接受胚胎的受体比例。FTET治疗方法的最新变化,如注射孕马血清促性腺激素(eCG),已提高了妊娠率,并为在农场更轻松地实施这些治疗提供了机会。

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