Fuse H, Mizuno I, Nagakawa O, Kazama T, Terada T, Katayama T, Masuda S
Department of Urology, Faculty of Medicine, Toyama Medical and Pharmaceutical University.
Hinyokika Kiyo. 1990 Jul;36(7):819-22.
A 64-year-old female with hypertension, hypokalemia visited our hospital. Endocrinological examinations showed a low level of plasma renin activity and high level of plasma aldosterone. Circadian rhythmicity of plasma aldosterone level was recognized. No change in the plasma level of aldosterone was observed after loading of standing and administration of furosemide. Adrenal scintigraphy, adrenal venous aldosterone assay and CT scan revealed two tumors in the left adrenal. The diagnosis of primary aldosteronism by left adrenal tumors was made from the above findings. A left adrenalectomy was performed and pathological findings showed two adenomas, which had no capsule either and were surrounded by normal adrenocortical tissue. Blood pressure normalized after surgery and the plasma levels of aldosterone and plasma renin activity were normalized.
一名64岁患有高血压、低钾血症的女性前来我院就诊。内分泌检查显示血浆肾素活性水平低，血浆醛固酮水平高。认识到血浆醛固酮水平的昼夜节律性。站立负荷和给予呋塞米后，未观察到血浆醛固酮水平的变化。肾上腺闪烁显像、肾上腺静脉醛固酮测定和CT扫描显示左肾上腺有两个肿瘤。根据上述发现诊断为左肾上腺肿瘤所致原发性醛固酮增多症。进行了左肾上腺切除术，病理结果显示为两个腺瘤，均无包膜，被正常肾上腺皮质组织包围。术后血压恢复正常，血浆醛固酮水平和血浆肾素活性也恢复正常。
