Mäuser W S, Sandrock S, Kotzott L, Bonnemeier H
Universitätsklinikum Schleswig-Holstein, Campus Kiel, Klinik für Innere Medizin III, Kardiologie und Angiologie, Arnold-Heller-Str. 3, 24105, Kiel, Deutschland.
Herzschrittmacherther Elektrophysiol. 2012 Mar;23(1):27-32. doi: 10.1007/s00399-012-0169-y.
Sleep apnea syndromes (SAS) are highly prevalent in cardiovascular patients. Because diagnostics are cost and labor intensive, these patients often remain undiagnosed. For this reason, simple screening methods for SAS in daily clinical practice are very important. Standardized questionnaires are one way to screen patients, i.e., simple standardized questionnaires have been shown to be highly predictive in OSA, but not in CSA patients. Simple ambulatory screening devices use oxymetry and/or nasal flow to determine the apnea-hypopnea index (AHI). These devices have been shown to be highly effective in screening for OSA and CSA. In addition, algorithms that calculate the electrocardiography (ECG)-derived AHI using heart rate variability and/or QRS morphology from Holter ECG recordings are also promising. Especially the latter method could become a simple tool for cardiologists to screen for SAS in clinical routine.
睡眠呼吸暂停综合征（SAS）在心血管疾病患者中极为普遍。由于诊断成本高且耗费人力，这些患者常常未被诊断出来。因此，在日常临床实践中用于SAS的简单筛查方法非常重要。标准化问卷是筛查患者的一种方式，即简单的标准化问卷已被证明对阻塞性睡眠呼吸暂停（OSA）具有高度预测性，但对中枢性睡眠呼吸暂停（CSA）患者则不然。简单的动态筛查设备利用血氧饱和度测定和/或鼻气流来确定呼吸暂停低通气指数（AHI）。这些设备已被证明在筛查OSA和CSA方面非常有效。此外，利用动态心电图记录中的心率变异性和/或QRS波形态来计算心电图（ECG）衍生的AHI的算法也很有前景。尤其是后一种方法可能会成为心脏病专家在临床常规中筛查SAS的一种简单工具。
