Kim C J, Okada Y, Konishi T, Kounami T, Pak K, Tomoyoshi T, Kushima R
Department of Urology, Shiga University of Medical Science.
Hinyokika Kiyo. 1990 Sep;36(9):1085-8.
An 18-month-old boy was admitted in April, 1988 because of a penile mass which had been first noted at the age of one month. From nine months after birth, transient bleeding from the mass accompanied by pain had been occasionally noted. At the age of 14 months, the mass seemed to grow markedly. On physical examination, there was an irregularly shaped mass on the right side of the prepuce. It was palpated subcutaneously, soft in consistency and was 10 mm in diameter. It had a light-purple color. Upon surgery, the mass was found not to have originated from the cavernous body of the penis, so that it could be excised without difficulty. Histopathological diagnosis was cavernous hemangioma. Electron microscopic examination revealed findings suggestive of newly formed blood vessels such as abnormal cuboidal shape of endothelial cells and a high nucleocytoplasmic ratio. Immunohistochemical examination of factor VIII-related antigen was in homogeneously positive in vascular endothelial cells. To our knowledge, this is the twenty-eighth case reported in Japan.
一名18个月大的男孩于1988年4月入院，原因是阴茎肿物，该肿物在1个月大时首次被发现。自出生9个月后，偶尔会注意到肿物出现短暂出血并伴有疼痛。14个月大时，肿物似乎明显增大。体格检查发现，包皮右侧有一个形状不规则的肿物。可触及皮下肿物，质地柔软，直径为10毫米。肿物呈浅紫色。手术时发现肿物并非起源于阴茎海绵体，因此可以顺利切除。组织病理学诊断为海绵状血管瘤。电子显微镜检查发现了提示新形成血管的表现，如内皮细胞呈异常立方形以及核质比高。血管内皮细胞中VIII因子相关抗原的免疫组织化学检查呈均匀阳性。据我们所知，这是日本报告的第28例病例。
