Rocco M B
Mount Sinai Medical Center, Cleveland, Ohio 44106-4198.
Am J Cardiol. 1990 Nov 6;66(16):18G-21G. doi: 10.1016/0002-9149(90)90388-h.
Use of exercise tolerance testing and new techniques of ambulatory electrocardiographic monitoring to more objectively measure myocardial ischemia have enabled clinicians to better recognize the magnitude, timing and variable characteristics of transient ischemic events. These commonly occurring events in patients with coronary artery disease have a diurnal pattern strikingly similar to that reported for catastrophic cardiovascular events such as myocardial infarction, sudden cardiac death and stroke. Whether those factors that contribute to reversible ischemic events are similar to those causing infarction and sudden death has not been resolved. However, the parallel increase in morning activity for these related phenomena suggests that a better understanding of the triggers of reversible myocardial ischemia may help improve understanding of the causes of myocardial infarction and sudden cardiac death.
使用运动耐量测试和动态心电图监测新技术来更客观地测量心肌缺血，使临床医生能够更好地识别短暂性缺血事件的严重程度、发生时间和可变特征。这些在冠心病患者中常见的事件具有昼夜模式，与心肌梗死、心源性猝死和中风等灾难性心血管事件所报告的模式惊人地相似。导致可逆性缺血事件的因素是否与导致梗死和猝死的因素相似尚未得到解决。然而，这些相关现象在早晨活动中同时增加，这表明更好地理解可逆性心肌缺血的触发因素可能有助于增进对心肌梗死和心源性猝死原因的理解。
