Laron Zvi
Endocrinology & Diabetes Research Unit, Schneider Children's Medical Center and Sackler School of Medicine, Tel Aviv University, Israel.
Pediatr Endocrinol Rev. 2011 Dec;9(2):546-8.
During embryogenesis, the growth hormone-secreting cells (somatotrophs) and the prolactin-secreting cells (lactotrophs) develop from a common progenitor cell (somatomammotroph). Postnatally, in situations when one of these two hormones is oversecreted, often the second hormone is, too. The question posed is whether the increased secretion of growth hormone together with that of prolactin over long periods of time is a risk factor for malignancy.
在胚胎发生过程中，分泌生长激素的细胞（生长激素细胞）和分泌催乳素的细胞（催乳激素细胞）由共同的祖细胞（生长催乳素细胞）发育而来。出生后，在这两种激素之一分泌过多的情况下，另一种激素通常也会分泌过多。提出的问题是，长期生长激素与催乳素分泌增加是否是恶性肿瘤的危险因素。
